Nutrigenetics and Nutrigenomics
Nutritional and genetic epidemiology
Gene by environment interaction
How uric acid affects the human body
Our group’s research interests are focused on understanding the effects of genetic and environmental factors and their interaction on complex human diseases using a combination of statistical, molecular and bioinformatics approaches. The specific interests include understanding the influence of genetic variants on serum uric acid levels (a biomarker for renal-cardiovascular disease), effect of gene by diet interactions on serum uric acid levels and associated renal-cardiovascular disease risk factors and identification of functional variants affecting these disorders that will lead to novel treatment options.
Other Research Focuses
Focus on nutritional genomics of complex diseases such as obesity, hypertension, type 2 diabetes, metabolic syndrome, and other chronic kidney disease (CKD) and cardiovascular disease (CVD) risk factors.This includes genetic risk of CKD and CVD in minority populations, and further investigating the gene-by-environment interaction influences (e.g. diet, physical activity, socio-demographic factors, ethnicity) on CKD/CVD outcomes.